A Biodegradability Evaluation and Simulation System (Bess), Applying and Discovering Knowledge of Biodegradation Pathways
نویسندگان
چکیده
We have previously reported on a software system called Bess which simulates the action of biodegradation pathways on compounds. It does so by encoding biodegradation pathways in a knowledge base and applying those pathways in sequence to the compound, breaking it down into metabolites. We describe Bess, its knowledge-base and the system that uses it, and some preliminary validation results. We also report on some modiications made to Bess to improve its performance and on investigation into how genetic algorithm learning can be used to discover new biodegradation knowledge.
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